AFB diagnostics rely on
a basic digestion-decontamination and an effective neutralization
process to eliminate non-mycobacterial organisms from
patient samples. Although an elevated pH will kill other
organisms first, mycobacteria will quickly succumb if
exposed to this basic environment for too long. Alpha-Tec
Systems' Mycobacteriology System has dramatically improved
the ability of laboratories to recover accurate positive
AFB specimens and reduce the occurrence of contaminated
/ reprocessed samples by rigidly controlling pH throughout
the specimen preparation process.
Industry
standard reagents do not effectively control pH
M/15 phosphate
buffer is unable to effectively neutralize NaOH
An elevated
pH will begin killing AFB after 20 minutes of exposure
Exposure
during centrifugation can cause significant AFB
die-off
AFB die-off reduces the effectiveness of detection diagnostics
The Alpha-Tec
Systems Mycobacteriology System is the only available
reagent set proven to effectively control pH and prevent
mycobacterial die-off.